Antibiotics damage the gut microbiome, which can result in overgrowth of pathogenic microorganisms and emergence of antibiotic resistance.Inactivation of antibiotics in the small intestine represents a novel strategy to protect the colonic microbiota.SYN-004 (ribaxamase) is a beta-lactamase formulated for oral delivery intended to degrade intraveno
Novel MRI contrast methods, such as Chemical Exchange Saturation Girls Pants Transfer (CEST), rely on previously developed theory and approaches, often introduced first in solidstate NMR.Understanding or at least connecting the basic principles and original works to the modern-day contrast methods in MRI is instructive.The work brings together conc
Low adherence with prescribed Brush treatments is very common in chronic diseases and represents a significant barrier to optimal management, with both clinical and economic consequences.In chronic obstructive pulmonary disease (COPD), poor adherence, also in terms of premature discontinuation of therapy or improper use of inhaler devices, leads to